Research Article on Formulation and Evaluation of Syrup Using Fenugreek and Bay Leaves for The Treatment of Diabetic Wound Healing

Diabetes mellitus impairs wound healing due to chronic inflammation, poor circulation, and increased susceptibility to infection. This study aimed to develop a herbal syrup formulation incorporating fenugreek (Trigonella foenum-graecum) and bay leaves (Laurus nobilis)—both known for their antioxidant, anti-inflammatory, and hypoglycemic properties—to support wound healing in diabetic individuals. The syrup was formulated using aqueous extracts of fenugreek seeds and bay leaves, combined with honey as a natural sweetener and stabilizer. Supplementary components such as citric acid, sodium benzoate, and ascorbic acid were added to enhance stability, shelf life, and therapeutic potential. The physicochemical characteristics of the syrup, including pH, viscosity, and microbial stability, were evaluated. Additionally, in vivo assessment using a diabetic rat model demonstrated improved wound closure rates, reduced inflammation, and enhanced tissue regeneration in groups treated with the herbal syrup, compared to untreated diabetic controls. These findings support the therapeutic potential of the formulated syrup as an adjunctive oral treatment for diabetic wound healing. The use of safe, plant-based ingredients presents an affordable and accessible alternative to conventional synthetic drugs. Further clinical trials are recommended to establish efficacy in human subjects and to optimize dosage regimens for clinical application.