Combined Metabolomic and Proteomic Analysis

The combined analysis of proteome and metabolome is an effective research strategy to systematically characterize the metabolic regulatory network of biological organisms. By normalizing and statistically analyzing the bulk data from proteome and metabolome, together with metabolic pathway enrichment and correlation analysis, molecular models of downstream metabolite changes and metabolic enzyme regulation mechanisms can be constructed. Rapidly screen the data to find differential proteins and differential metabolites that share a certain type of metabolic pathway or have the same change trend, systematically describe the molecular regulation mechanism in the organism, and provide data basis for subsequent experimental validation and analysis.