Pharmacognostic Standardization, Phytochemical Profiling, and Pharmacological Evaluation of Jasminum officinale L.: A Comprehensive Study

Jasminum officinale L. (Oleaceae), commonly known as common jasmine, has been traditionally employed in multiple medicinal systems. This study comprehensively evaluates its pharmacognostic characteristics, phytochemical constituents, and pharmacological properties, particularly its antioxidant and antibacterial activities. Methanolic extraction of the plant yielded 2.79% w/w extract. Pharmacognostic parameters such as ash values and moisture content confirmed the identity and quality of the crude drug. Phytochemical screening revealed the presence of multiple classes of secondary metabolites, with quantitative estimations showing notable levels of flavonoids, saponins, and alkaloids. LC-MS analysis identified major bioactive compounds including quercetin-3-O-glucoside, rutin, and luteolin derivatives. Antioxidant assays (DPPH and H2O2 scavenging) and antibacterial assays against five clinically significant bacterial strains established the moderate to strong bioactivity of the extract. The results support the traditional uses of J. officinale and highlight its potential as a source of novel bioactive compounds.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-08-10
DOI
https://doi.org/10.5281/zenodo.16789643
Primary Topic
Phytochemicals and Antioxidant Activities
Type
article
Field-Weighted Citation Impact
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article

Pharmacognostic Standardization, Phytochemical Profiling, and Pharmacological Evaluation of Jasminum officinale L.: A Comprehensive Study

Zenodo (CERN European Organization for Nuclear Research)
Phytochemicals and Antioxidant Activities
article

Pharmacognostic Standardization, Phytochemical Profiling, and Pharmacological Evaluation of Jasminum officinale L.: A Comprehensive Study

article en

Abstract

Jasminum officinale L. (Oleaceae), commonly known as common jasmine, has been traditionally employed in multiple medicinal systems. This study comprehensively evaluates its pharmacognostic characteristics, phytochemical constituents, and pharmacological properties, particularly its antioxidant and antibacterial activities. Methanolic extraction of the plant yielded 2.79% w/w extract. Pharmacognostic parameters such as ash values and moisture content confirmed the identity and quality of the crude drug. Phytochemical screening revealed the presence of multiple classes of secondary metabolites, with quantitative estimations showing notable levels of flavonoids, saponins, and alkaloids. LC-MS analysis identified major bioactive compounds including quercetin-3-O-glucoside, rutin, and luteolin derivatives. Antioxidant assays (DPPH and H2O2 scavenging) and antibacterial assays against five clinically significant bacterial strains established the moderate to strong bioactivity of the extract. The results support the traditional uses of J. officinale and highlight its potential as a source of novel bioactive compounds.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 56%
Phytochemicals and Antioxidant Activities
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