Current Advances in the Management of Diabetes Mellitus

Diabetes mellitus (DM) is a growing epidemic that is causing a significant socioeconomic burden on nations all over the world. Since traditional treatment approaches have not fully addressed the underlying causes of the disease and are fraught with serious side effects, new treatment options for the management of diabetes mellitus are developing quickly. Thus, this narrative review explores different treatment regimens in DM management and the associated challenges. A literature search for pub - lished articles on recent advances in DM management was completed with search engines including Web of Science, Pubmed /Medline, Scopus, using keywords such as DM, management of DM, and gene therapy. According to our research, significant advancements have been made in the treatment of diabetes mellitus, with encouraging outcomes when employing various treatment approaches such as gene therapy, nanotechnology, stem cells, medical nutrition therapy, and lifestyle change. Numerous obstacles have been faced when employing these methods, such as optimizing them to guarantee the best possible glycemic, lipid, and blood pressure control to reduce complications, enhancing patient adherence to pharmacologic and lifestyle interventions, safety, ethical concerns, and an efficient delivery system, among other things. In conclusion, an efficient and secure clinical treatment strategy depends on lifestyle management in addition to pharmaceutical treatments and the optimization of these strategies.