A Simple Review of Analytical Techniques for Determination of Vildagliptin

A associate of the novel class of hypoglycemia medications known as dipeptidylpeptidase-4 (DPP-4) inhibitors is the oral medication vildagliptin.1 It is used to manage type II diabetes mellitus, a condition in which insulinotropic effects and GLP-1 emission are compromised.3 Glucagon-like peptide 1 (GLP-1) and glucose-subordinate insulinotropic polypeptide (GIP), incretin molecules that promote insulin release and regulate blood glucose levels, are degraded by vildagliptin through the suppression of DPP-4.The methods described in this article include high-performance liquid chromatography. High-performance liquid chromatography techniques have been widely employed, as may be observed. As a result, this study will assist in the selection and development of appropriate analytical approaches to estimate vidagliptin and produce satisfactory outcomes. Researchers occupied in the field of Vildagliptin analytical research may find the investigatory review to be a useful resource for detailed information on different analytical techniques such as Capillary Electrophoresis, Uv Spectrophotometer, RP HPLC, HPTLC and their experimental conditions.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-04-22
DOI
https://doi.org/10.5281/zenodo.15264827
Primary Topic
Diabetes Treatment and Management
Type
article
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article

A Simple Review of Analytical Techniques for Determination of Vildagliptin

Zenodo (CERN European Organization for Nuclear Research)
Diabetes Treatment and Management
article

A Simple Review of Analytical Techniques for Determination of Vildagliptin

article en

Abstract

A associate of the novel class of hypoglycemia medications known as dipeptidylpeptidase-4 (DPP-4) inhibitors is the oral medication vildagliptin.1 It is used to manage type II diabetes mellitus, a condition in which insulinotropic effects and GLP-1 emission are compromised.3 Glucagon-like peptide 1 (GLP-1) and glucose-subordinate insulinotropic polypeptide (GIP), incretin molecules that promote insulin release and regulate blood glucose levels, are degraded by vildagliptin through the suppression of DPP-4.The methods described in this article include high-performance liquid chromatography. High-performance liquid chromatography techniques have been widely employed, as may be observed. As a result, this study will assist in the selection and development of appropriate analytical approaches to estimate vidagliptin and produce satisfactory outcomes. Researchers occupied in the field of Vildagliptin analytical research may find the investigatory review to be a useful resource for detailed information on different analytical techniques such as Capillary Electrophoresis, Uv Spectrophotometer, RP HPLC, HPTLC and their experimental conditions.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 44%
Diabetes Treatment and Management
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A Simple Review of Analytical Techniques for Determination of Vildagliptin · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS