Effect of GERD on response to asthma treatment: A literature review

Asthma and Gastroesophageal Reflux Disease (GERD) are two conditions that are often found together, with the prevalence of GERD in asthma patients being higher than in the general population. The pathophysiological relationship between these two conditions is complex and influences each other. GERD can worsen asthma symptoms, increase the frequency of exacerbations, and reduce the effectiveness of asthma treatment. On the other hand, asthma can also worsen GERD symptoms through the mechanism of increased intra-abdominal pressure and the side effects of certain asthma medications. This literature explores pathophysiological mechanisms, the influence of GERD on asthma treatment, and management strategies that can improve asthma control. However, further research is needed to clarify the mechanism of the relationship between these two conditions and optimize treatment strategies.