Efectividad del láser CO2 asociado a factores de crecimiento plaquetario en la terapia del acrocordón gigante vulvar. Reporte de un caso.

Vulvar acrochordon, a benign epithelial tumor, has a low prevalence and an unknown etiology, although it is often associated with obesity and type II diabetes mellitus. While management is typically conservative, alternative therapeutic methods, such as fractional carbon dioxide (CO2) laser combined with autologous platelet-rich plasma (PRP), are available for the treatment of this condition. This case study evaluated the therapeutic efficacy of fractional CO2 laser combined with PRP for the treatment of giant vulvar acrochordon in a 32-year-old nulligravid patient with a body mass index (BMI) of 21.6 kg/m². The patient presented with a mobile vulvar tumor measuring 18cm x 15cm on the right labia majora, characterized as pedunculated (7cm x 3cm), multilobulated, lobules of varying sizes and a rough surface texture, enhanced vascularization at its base and distal ulcerated lesions. The lesion was non-painful upon examination and had persisted over a four-year period. Following informed consent, the patient underwent in-office pedicle resection under local anesthesia using fractional CO2 laser at a power setting of 5 to 7 watts, along with two sessions of PRP application. Postoperative evaluations conducted at 72 hours, 9 days, and one month following PRP administration demonstrated favorable outcomes, including satisfactory wound healing, improved vulvar aesthetics, and enhanced patient self-esteem. This study concludes that combined treatment of fractional CO2 laser and PRP represents an effective therapeutic approach for the eradication of giant vulvar acrochordon, as demonstrated by the wound healing process and aesthetic vulvar remodeling.