Formulation And Evolution of Fast Dissolving Tablet Containing Nanoparticle Poorly Water-Soluble Drug

In recent decades, a range of pharmaceutical research has been done to develop new dosage forms. Among the dosage forms designed to aid ease of treatment, the rapid disintegrating tablet (RDT) is one of the most commonly deployed commercial goods. Formulating these compounds as pure drug nanoparticles is one of the newer drug-delivery strategies applied to this class of molecules. Nanoparticle dispersions are stable and have a mean diameter of less than 1 micron. The formulations consist of water, drug, and one or more generally regarded as safe excipients. These formulations offer a chance to expand the product line because many senior people will have trouble using traditional oral dose forms (such as tablets, capsules, suspensions, and solutions) due to hand tremors and dysphagia. Young people frequently have difficulty swallowing due to their immature neurological and muscular systems. The mentally ill, the developmentally handicapped, patients who are recalcitrant, on decreased liquid-intake plans, or who are queasy are additional categories who may have issues with traditional oral dosage forms.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-05-18
DOI
https://doi.org/10.5281/zenodo.15458340
Primary Topic
Drug Solubulity and Delivery Systems
Type
article
Field-Weighted Citation Impact
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article

Formulation And Evolution of Fast Dissolving Tablet Containing Nanoparticle Poorly Water-Soluble Drug

Zenodo (CERN European Organization for Nuclear Research)
Drug Solubulity and Delivery Systems
article

Formulation And Evolution of Fast Dissolving Tablet Containing Nanoparticle Poorly Water-Soluble Drug

article en

Abstract

In recent decades, a range of pharmaceutical research has been done to develop new dosage forms. Among the dosage forms designed to aid ease of treatment, the rapid disintegrating tablet (RDT) is one of the most commonly deployed commercial goods. Formulating these compounds as pure drug nanoparticles is one of the newer drug-delivery strategies applied to this class of molecules. Nanoparticle dispersions are stable and have a mean diameter of less than 1 micron. The formulations consist of water, drug, and one or more generally regarded as safe excipients. These formulations offer a chance to expand the product line because many senior people will have trouble using traditional oral dose forms (such as tablets, capsules, suspensions, and solutions) due to hand tremors and dysphagia. Young people frequently have difficulty swallowing due to their immature neurological and muscular systems. The mentally ill, the developmentally handicapped, patients who are recalcitrant, on decreased liquid-intake plans, or who are queasy are additional categories who may have issues with traditional oral dosage forms.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 61%
Drug Solubulity and Delivery Systems
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