Formulation and Evaluation of Herbal Antifungal Ointment

The rising resistance of harmful fungi to traditional antifungal medications has sparked a growing interest in natural remedies. This study aims to formulate and evaluate a topical herbal anti-fungal ointment using extracts from Melia Azedarach (chinaberry) and Hygrophila Auriculata (marsh barbel), Both known for their traditional medicinal properties. Ethanolic extracts of the plant materials was prepared and incorporated into an ointment base using standard methods. Then formulation was evaluated for physicochemical properties like pH, Spreadability, stability, and homogeneity. Antifungal activity was checked using the agar well diffusion method (MIC) against common fungus such as Candida albicans and Aspergillus niger. The formulated ointment showed promising antifungal effect, comparable to standard antifungal agents, and has favorable physical characteristics and stability when checked for 30 days’ time period. These evaluations support the potential of Chinaberry and Marsh Barbel extracts as effective herbal ingredients in topical antifungal formulations, and can be used to treat various fungal infections.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-06-30
DOI
https://doi.org/10.5281/zenodo.15773130
Primary Topic
Phytochemical compounds biological activities
Type
article
Field-Weighted Citation Impact
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article

Formulation and Evaluation of Herbal Antifungal Ointment

Zenodo (CERN European Organization for Nuclear Research)
Phytochemical compounds biological activities
article

Formulation and Evaluation of Herbal Antifungal Ointment

article en

Abstract

The rising resistance of harmful fungi to traditional antifungal medications has sparked a growing interest in natural remedies. This study aims to formulate and evaluate a topical herbal anti-fungal ointment using extracts from Melia Azedarach (chinaberry) and Hygrophila Auriculata (marsh barbel), Both known for their traditional medicinal properties. Ethanolic extracts of the plant materials was prepared and incorporated into an ointment base using standard methods. Then formulation was evaluated for physicochemical properties like pH, Spreadability, stability, and homogeneity. Antifungal activity was checked using the agar well diffusion method (MIC) against common fungus such as Candida albicans and Aspergillus niger. The formulated ointment showed promising antifungal effect, comparable to standard antifungal agents, and has favorable physical characteristics and stability when checked for 30 days’ time period. These evaluations support the potential of Chinaberry and Marsh Barbel extracts as effective herbal ingredients in topical antifungal formulations, and can be used to treat various fungal infections.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 60%
Phytochemical compounds biological activities
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