Dubin Johnson Syndrome and the Enigma Surrounding Conjugated Hyperbilirubinemia in Pregnancy: A Case Report

1.1. Aim and Background: Jaundice in pregnancy is an uncommon condition. The aim is to diagnose a rare congenital hepatic disorder- Dubin Johnson Syndrome and elucidate an algorithm to arrive at it thus sensitizing the readers to unconventional diagnoses encountered while dealing with a case of jaundice in pregnancy. 1.2. Case Description: We present the case of a 27-year-old antenatal patient with unexplained conjugated hyperbilirubinemia exacerbating with every pregnancy in whom a set of comprehensive albeit feasible clinical tests helped to conclusively settle at the diagnosis of DJS. 1.3. Conclusion: More often benign than not, DJS is a rare entity with no risk of fibrosis progression, cirrhosis or adverse perinatal outcomes. 1.4. Clinical Significance: It is imperative to diagnose DJS not only to differentiate it from other pre-existing or concurrent hepatic disorders in pregnancy considerably impacting management strategies and foetal-maternal outcomes but also to reassure the patient of its benign course, an essential element of good clinical practice.