Simultaneous Estimation of Fluconazole and Zinc Pyrithione By Uv Spectroscopy

Analytical method development is an approach to select an appropriate assay procedure to determine the composition of various formulations, to prove that particular analytical method is acceptable for use in pharmaceutical laboratories. By keeping all the major questions in mind present methodical evolution of analytical method development and validation is done, in which UV-spectroscopic methods are elaborated. Method development for simultaneous estimation of Zinc Pyrithione and Fluconazole was done in the present study. Literature review revealed that not a single method is reported for the simultaneous estimation of both the drugs in tablet dosage form.In UV-Spectroscopic method of analysis for multicomponent system, simultaneous estimation method was performed and validation of method was done as per ICH guidelines. The developed method is accurate, precise, convenient, in expensive and reproducible hence can be used for the routine analysis.