Novel Pharamacology Approaches of Migraine Therapy

Millions of people worldwide suffer from migraines, a crippling neurological condition. Traditional treatments often provide inadequate relief, underscoring the need for innovative pharmacological approaches. Novel drugs and targets in migraine treatment are highlighted in this review.Although the need for new therapeutic approaches to treat migraine and other primary headaches is well acknowledged,underlying mechanism & the molecular targets that should be tackled Although new medications are still unknown, there have been notable advancements in the previous ten years in the treatment of migraines, including the discovery of substances that exactly stop migraine attacks targeting .Because current acute and preventive therapies are either ineffective [or] poorly tolerated, the management of migraine patients is frequently inadequate. The only options for treating acute migraine attacks have been analgesics, analgesic combinations with caffeine, ergotamines, and triptans. non-invasive & invasive neruomodulation approaches also show promise as both acute & preventive therapies ,although further studies are needed to define appropriate candidates for these therapies & optium protocols for their use.