Low Carbohydrate and High Fat or Keto Diet Effect on HbA1c Levels in Type 2 Diabetics

Objective: To know the impact of Low carbohydrate and high fat or Keto diet effect on Hb1C levels in patients with Type 2 diabetics. Participants with type2 diabetes restrict their carbohydrate intake to 30g or less daily, increase fat, and maintain a modest but not high protein intake to induce a state referred to as “nutritional ketosis”. Material and Method: 130 type2 DM patient with HbA1c level 7.8%±1.3, mean glucose level 169md/dl ±31 are made to follow Low carbohydrate and high fat diet for 3months of duration HbA1c level are estimated. Result: After 3months of follow up 15 dropouts 5 no effect remaining 110 show decrease in HbA1c level to 6.43%±1.47 & mean glucose level 137mg/dl±28, p value <0.0010 shows significant variation, linear regression for HbA1c –r2: 0.53, glucose r2: 0.49. Conclusion: No adverse effects except mild constipation. Patients on drugs decreased usage from 3 to 1 or nil at 3months. In summary Low carbohydrate and high fat diet over 3 months led to a remarkable reduction in HbA1c levels, it lead to greater improvements in symptoms associated with type II diabetes.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-11-26
DOI
https://doi.org/10.5281/zenodo.14599589
Primary Topic
Diet and metabolism studies
Type
article
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article

Low Carbohydrate and High Fat or Keto Diet Effect on HbA1c Levels in Type 2 Diabetics

Zenodo (CERN European Organization for Nuclear Research)
Diet and metabolism studies
article

Low Carbohydrate and High Fat or Keto Diet Effect on HbA1c Levels in Type 2 Diabetics

article en

Abstract

Objective: To know the impact of Low carbohydrate and high fat or Keto diet effect on Hb1C levels in patients with Type 2 diabetics. Participants with type2 diabetes restrict their carbohydrate intake to 30g or less daily, increase fat, and maintain a modest but not high protein intake to induce a state referred to as “nutritional ketosis”. Material and Method: 130 type2 DM patient with HbA1c level 7.8%±1.3, mean glucose level 169md/dl ±31 are made to follow Low carbohydrate and high fat diet for 3months of duration HbA1c level are estimated. Result: After 3months of follow up 15 dropouts 5 no effect remaining 110 show decrease in HbA1c level to 6.43%±1.47 & mean glucose level 137mg/dl±28, p value <0.0010 shows significant variation, linear regression for HbA1c –r2: 0.53, glucose r2: 0.49. Conclusion: No adverse effects except mild constipation. Patients on drugs decreased usage from 3 to 1 or nil at 3months. In summary Low carbohydrate and high fat diet over 3 months led to a remarkable reduction in HbA1c levels, it lead to greater improvements in symptoms associated with type II diabetes.

Zenodo (CERN European Organization for Nuclear Research)
Institute of Medical Sciences (IN)
Zero hunger
Openalex Percentile: Top 58%
Diet and metabolism studies
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