GENETIC PREDISPOSITION TO PERIODONTAL DISEASES: MYTH OR REALITY?

GENETIC PREDISPOSITION TO PERIODONTAL DISEASES: MYTH OR REALITY? Yusupjanova Nigora Davrbek qizi assistant at Central Asian Medical University in Fergana https://doi.org/10.5281/zenodo.15133668 Abstract: Periodontal diseases, including gingivitis and periodontitis, are among the most prevalent oral health conditions worldwide. While bacterial infections are considered the primary cause, increasing evidence suggests a genetic component in disease susceptibility. This article explores the role of genetic predisposition in periodontal diseases through a comprehensive analysis of family-based studies, twin studies, genome-wide association studies (GWAS), and epigenetic influences. The findings highlight that while genetics play a role, environmental and behavioral factors significantly modulate disease expression. The implications of genetic research for personalized periodontal treatment are also discussed. Keywords: Periodontal diseases, genetic predisposition, GWAS, periodontitis, hereditary factors.