THE USE OF ISOTRETINOIN FOR TREATING MODERATE-TO-SEVERE AND NODULOCYSTIC ACNE

This article presents data on the pathogenesis of acne, therapeutic decision-making mechanisms, the strategy for prescribing isotretinoin, and further patient management. It addresses key questions regarding the appropriate daily dosage and the importance of achieving the cumulative dose, as well as the safety profile of isotretinoin-containing medications. The article also discusses the use of high-dose vitamin A (retinol palmitate) in acne patients and the associated adverse effects. Three clinical cases of patients diagnosed with acne are presented to illustrate treatment strategies.