Serum Lipid Profile of Women with Pregnancy Induced Hypertension and Normal Pregnancy : A Comparative Study

Background: Pregnancy induced hypertension is a major cause of fetomaternal morbidity. Studies have shown alteration of serum lipid metabolism in PIH which occur early and may help predicting PIH. The aim of the study was to compare the serum lipid levels in women with pregnancy induced hypertension and normal pregnancy. Methods: This case control study was conducted in the Department of Obstetrics and Gynaecology, Darbhanga Medical College and Hospital, Laheriasarai, Bihar from January 2023 to June 2023. A total of 100 (one hundred) were selected, out of which 50 (fifty) normotensive pregnant women served as a control and 50 (fifty) hypertensive women constituted the study group. Besides baseline routine investigations, estimation of Serum lipid profile was done by collecting blood samples from antecubital vein of every case and control and were analysed at department of Biochemistry, DMCH, Laheriasarai, Bihar. Results: The hypertensive group had a significant rise in Triglyceride (TG), total cholesterol, LDL-C levels and decreased HDL-C levels as compared to the control group. Conclusion: Abnormal lipid profile during pregnancy plays an important role in development of pre-eclampsia.