THE ROLE OF NON-STEROID ANTI-INFLAMMATORY DRUGS IN ENTEROPATHY IN PATIENTS (REVIEW ARTICLE)

Resume. Enteropathy is a common condition in patients with rheumatic diseases, which can develop secondarily due to the disease itself or drugs used in treatment. Patients with rheumatoid arthritis are one of the pressing problems of modern medicine. The prevalence and frequency of gastrointestinal inflammation in rheumatoid arthritis risk factors for chronic gastrointestinal disease (GIT) are more common than in diagnosed rheumatoid arthritis. As a result, early diagnosis of gastrointestinal inflammation in patients with rheumatoid arthritis has important clinical and prognostic significance. Also, the occurrence of chronic inflammation in rheumatoid arthritis primarily depends on the duration of the disease and the nature of the inflammation. An analysis of current data on concomitant conditions in rheumatoid arthritis (RA) is presented. Risk factors and pathogenetic interrelation of RA with enteropathic diseases have been identified. Prolonged use of nonsteroidal anti-inflammatory drugs indicates a negative effect on the mucous membrane of the gastrointestinal tract, which leads to erosive and ulcerative inflammation of the upper mucosa in patients with RA. Key words: Enteropathy, rheumatoid arthritis, chronic inflammation, dyspepsia, gastrointestinal tract, chronic enteritis.