The Influence of Physical Activity on Perceived Stress in Thyroid Patients in India

Abstract Thyroid disorders, including hypothyroidism and hyperthyroidism, are among the most prevalent endocrine conditions in India, often leading to persistent psychological symptoms such as perceived stress. While pharmacological treatments address hormonal imbalances, many patients continue to experience emotional distress. This study investigates the relationship between physical activity and perceived stress among Indian thyroid patients, aiming to explore the potential of exercise as a nonpharmacological intervention. A cross-sectional design was used to assess 120 adults with clinically diagnosed thyroid disorders, utilizing the International Physical Activity Questionnaire (IPAQ) and the Perceived Stress Scale (PSS). Participants were categorized into three age groups to explore age-related variations. Results indicated a significant negative correlation between physical activity and perceived stress, particularly among young and middle-aged adults. Moderate physical activity levels were most effective in reducing stress. Findings align with the biopsychosocial model and support theories such as allostatic load and HPA axis regulation, suggesting that exercise modulates neuroendocrine responses linked to stress. This study underscores the importance of integrating physical activity into thyroid care, especially in culturally sensitive and resource-constrained settings like India. It advocates for holistic, age-appropriate interventions to improve psychological well-being alongside physical health in thyroid patients.