INTEGRATED APPROACH TO THE DIAGNOSIS AND MANAGEMENT OF POLYCYSTIC OVARY SYNDROME (PCOS) IN REPRODUCTIVE-AGE WOMEN: A CLINICAL AND METABOLIC PERSPECTIVE

Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine and metabolic disorder affecting women of reproductive age, with implications for fertility, metabolic health, and psychosocial well-being. Despite its widespread occurrence, the condition remains underdiagnosed and undertreated due to its variable clinical presentation. The significance of this thesis lies in the rising prevalence of PCOS in Uzbekistan and globally, its impact on women's health, and the growing need for integrated, multidisciplinary management strategies. Polycystic Ovary Syndrome (PCOS) is one of the most common endocrine disorders affecting women of reproductive age worldwide, with an estimated prevalence ranging from 8% to 13%, depending on diagnostic criteria and population studied. In Uzbekistan, as in many developing countries, the growing prevalence of lifestyle-associated metabolic syndromes such as obesity, insulin resistance, and type 2 diabetes has brought increased attention to PCOS as a major public health concern.