The current situation of antibiotic use in the orthopedic trauma department of the Central Highlands Regional General hospital in 2024

The irrational use of antibiotics leads to an increase of antibiotic resistance, as well as rising costs of hospitalization and reduced treatment effectiveness. Our study aims to assess the usage of antibiotics in the Department of Trauma and Orthopedics at The Central Highlands Regional General Hospital. A prospective cross-sessional study was conducted over six months on antibiotic utilization in adult inpatients from February 2024 to July 2024. The data were evaluated using Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/ DDD) methodology, the Drug Utilization 90% (DU90%) Index, and the World Health Organization’s Access, Watch and Reserve (WHO AWaRe) classification. The study findings revealed that antibiotics were primarily administered through injection, comprising 99.44% of total usage. Furthermore, antibiotics were exclusively utilized in the generic category, with domestically produced drugs representing a significant portion of the total usage value (72.11%). Beta-lactams accounted for the highest proportion of antibiotic consumption (57.50% of total expenditure). The highest proportions of the DDD/100 bed-days belonged to netilmicin (29.19%), ceftriaxone (27.29%), and cloxacillin (24.27%). The beta-lactams and aminoglycosides had the highest DDD/100 bed-days proportions at 36.97% and 23.00%, respectively. Among the beta-lactams, third-generation cephalosporins accounted for highest DDD/100 bed-days proportion (17.20%). Within the DU90% segment, antibiotics belonged to the Access list were gentamicin and cloxacillin, accounting for 31.58%, while antibiotics belonged to the Watch list included netilmicin, ceftriaxone and ciprofloxacin, accounting for 61.06%.