Etiology, Pathophysiology, Histpathophysiology of Niacin Deficiency and Risk Factors for Developing Niacin Deficiency

Niacin (vitamin B3) deficiency results in a condition known as pellagra. Pellagra includes the triad of dermatitis, dementia, and diarrhea and can result in death. In addition, niacin deficiency can occur through genetic disorders, malabsorptive conditions, and interaction with certain medications. Today, niacin deficiencies are uncommon in industrialized nations primarily due to sufficient dietary intake; however, specific populations remain at risk of this mostly eradicated condition. Today, niacin deficiencies are uncommon in industrialized nations primarily due to sufficient dietary intake; however, specific populations remain at risk of this mostly eradicated condition. In addition to reviewing the diagnosis and treatment of niacin insufficiency, this activity emphasizes the importance of the interprofessional team in diagnosing and managing individuals with this illness.