EFFECTIVENESS OF PROPHYLACTIC USE OF TAMSULOSIN FOR THE PREVENTION OF URINARY RETENTION FOLLOWING SURGERIES UNDER SPINAL ANAESTHESIA

Background:Postoperative urinary retention (POUR) is a common complicationfollowing surgeries under spinal anesthesia, leading to patient discomfort, delayedmobilization, and increased risk of catheterization. Tamsulosin, a selective α1Aadrenergic receptor blocker, has been shown to reduce bladder outlet resistance andmay help prevent POUR.Objective: To evaluate the effectiveness of prophylactic tamsulosin in preventingpostoperative urinary retention in patients undergoing elective surgeries under spinalanesthesia.Methods: This prospective, observational, comparative cross-sectional study wasconducted at the Department of General Surgery, GIMS, Gadag, over 18 months(August 2023–February 2025). A total of 150 patients aged 18–60 years scheduledfor elective surgery under spinal anesthesia were randomly allocated into two groups.Group A received tamsulosin 0.4 mg 14 hours, 2 hours before surgery, and 6 hourspostoperatively; Group B received standard preoperative care without tamsulosin.The incidence of POUR was assessed based on suprapubic discomfort, palpablemass, inability to void within 12 hours, and requirement of catheterization.Results: POUR occurred in only 1 patient (1.33%) in the tamsulosin group comparedto 13 patients (17.33%) in the placebo group (p = 0.0007). Similarly, catheterizationwas required in 1.33% of patients in the tamsulosin group versus 17.33% in theplacebo group. No statistically significant differences were noted in baselinecharacteristics such as age, serum creatinine, or prostate volume between the groups.Conclusion: Prophylactic administration of tamsulosin significantly reduces theincidence of postoperative urinary retention and catheterization in patientsundergoing surgeries under spinal anesthesia. Its inclusion in perioperative protocolscould enhance postoperative recovery and patient comfort.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-08-13
DOI
https://doi.org/10.5281/zenodo.16831948
Primary Topic
Urinary Tract Infections Management
Type
article
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article

EFFECTIVENESS OF PROPHYLACTIC USE OF TAMSULOSIN FOR THE PREVENTION OF URINARY RETENTION FOLLOWING SURGERIES UNDER SPINAL ANAESTHESIA

Zenodo (CERN European Organization for Nuclear Research)
Urinary Tract Infections Management
article

EFFECTIVENESS OF PROPHYLACTIC USE OF TAMSULOSIN FOR THE PREVENTION OF URINARY RETENTION FOLLOWING SURGERIES UNDER SPINAL ANAESTHESIA

article en

Abstract

Background:Postoperative urinary retention (POUR) is a common complicationfollowing surgeries under spinal anesthesia, leading to patient discomfort, delayedmobilization, and increased risk of catheterization. Tamsulosin, a selective α1Aadrenergic receptor blocker, has been shown to reduce bladder outlet resistance andmay help prevent POUR.Objective: To evaluate the effectiveness of prophylactic tamsulosin in preventingpostoperative urinary retention in patients undergoing elective surgeries under spinalanesthesia.Methods: This prospective, observational, comparative cross-sectional study wasconducted at the Department of General Surgery, GIMS, Gadag, over 18 months(August 2023–February 2025). A total of 150 patients aged 18–60 years scheduledfor elective surgery under spinal anesthesia were randomly allocated into two groups.Group A received tamsulosin 0.4 mg 14 hours, 2 hours before surgery, and 6 hourspostoperatively; Group B received standard preoperative care without tamsulosin.The incidence of POUR was assessed based on suprapubic discomfort, palpablemass, inability to void within 12 hours, and requirement of catheterization.Results: POUR occurred in only 1 patient (1.33%) in the tamsulosin group comparedto 13 patients (17.33%) in the placebo group (p = 0.0007). Similarly, catheterizationwas required in 1.33% of patients in the tamsulosin group versus 17.33% in theplacebo group. No statistically significant differences were noted in baselinecharacteristics such as age, serum creatinine, or prostate volume between the groups.Conclusion: Prophylactic administration of tamsulosin significantly reduces theincidence of postoperative urinary retention and catheterization in patientsundergoing surgeries under spinal anesthesia. Its inclusion in perioperative protocolscould enhance postoperative recovery and patient comfort.

Zenodo (CERN European Organization for Nuclear Research)
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Urinary Tract Infections Management
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