Role of Nutrients in Diabetes

As a complicated metabolic disease, diabetes mellitus (DM) requires careful nutritional management to maximize glycemic control and minimize complications. With a focus on dietary fiber, gut microbiota, macronutrients, and micronutrients, this review article examines the critical role that nutrients play in the prevention and treatment of diabetes. Through a variety of processes, such as insulin sensitivity and glucose metabolism, macronutrients like proteins, carbs, and fats affect glycemic control. It is emphasized how crucial micronutrients—such as vitamins and trace minerals like copper, zinc, and manganese—are in regulating inflammatory and oxidative stress pathways. The review also covers how dietary fiber affects the composition of the gut microbiota and how it may help diabetes patients' metabolic health by increasing insulin secretion and short-chain fatty acid synthesis. Nutritional measures to avoid frailty and sarcopenia are the main focus of special considerations for older diabetic patients. In order to attain the best possible results for managing diabetes, the review also emphasizes the importance of customized dietary approaches that take individual metabolic objectives, cultural norms, and financial constraints into account.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-02-23
DOI
https://doi.org/10.5281/zenodo.14914111
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
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article

Role of Nutrients in Diabetes

Zenodo (CERN European Organization for Nuclear Research)
Gut microbiota and health
article

Role of Nutrients in Diabetes

article en

Abstract

As a complicated metabolic disease, diabetes mellitus (DM) requires careful nutritional management to maximize glycemic control and minimize complications. With a focus on dietary fiber, gut microbiota, macronutrients, and micronutrients, this review article examines the critical role that nutrients play in the prevention and treatment of diabetes. Through a variety of processes, such as insulin sensitivity and glucose metabolism, macronutrients like proteins, carbs, and fats affect glycemic control. It is emphasized how crucial micronutrients—such as vitamins and trace minerals like copper, zinc, and manganese—are in regulating inflammatory and oxidative stress pathways. The review also covers how dietary fiber affects the composition of the gut microbiota and how it may help diabetes patients' metabolic health by increasing insulin secretion and short-chain fatty acid synthesis. Nutritional measures to avoid frailty and sarcopenia are the main focus of special considerations for older diabetic patients. In order to attain the best possible results for managing diabetes, the review also emphasizes the importance of customized dietary approaches that take individual metabolic objectives, cultural norms, and financial constraints into account.

Zenodo (CERN European Organization for Nuclear Research)
Zero hunger
Openalex Percentile: Top 60%
Gut microbiota and health
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Role of Nutrients in Diabetes · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS