Formulation And Assessment of Oral Gel for The Treatment of Mouth Ulcer Using Extract from Jamun Seed Powder

A new era in the successful creation of controlled release formulations with many properties to offer an effective drug delivery mechanism began with the introduction of bilayer tablets. Bilayer tablets are superior to conventional mouthwash, sprays, and gels. Therefore, using a bilayer pill for analgesic and anti-inflammatory purposes is rather different. Two incompatible substances can be separated using bi-layer tablets, two treatments can be released successively, or sustained release tablets with an immediate release dose in the first layer and a maintenance dose in the second layer can be made. The flaws of a single layered tablet are addressed by the improved and practical bilayer tablet technology. In order to solve common bilayer issues such layer separation, inadequate hardness, imprecise individual layer control of weight, and cross contamination, this article discusses why Development and production of quality bi-layer tablets must be carried out on unique tablet presses due to issues with the layers, decreased yield, etc. thereby a high production output is needed, utilizing an altered tablet press may not be the best choice for producing a superior bilayer tablet under GMP conditions.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-05-21
DOI
https://doi.org/10.5281/zenodo.15478930
Primary Topic
Pharmacology and Nanomedicine Research
Type
article
Field-Weighted Citation Impact
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article

Formulation And Assessment of Oral Gel for The Treatment of Mouth Ulcer Using Extract from Jamun Seed Powder

Zenodo (CERN European Organization for Nuclear Research)
Pharmacology and Nanomedicine Research
article

Formulation And Assessment of Oral Gel for The Treatment of Mouth Ulcer Using Extract from Jamun Seed Powder

article en

Abstract

A new era in the successful creation of controlled release formulations with many properties to offer an effective drug delivery mechanism began with the introduction of bilayer tablets. Bilayer tablets are superior to conventional mouthwash, sprays, and gels. Therefore, using a bilayer pill for analgesic and anti-inflammatory purposes is rather different. Two incompatible substances can be separated using bi-layer tablets, two treatments can be released successively, or sustained release tablets with an immediate release dose in the first layer and a maintenance dose in the second layer can be made. The flaws of a single layered tablet are addressed by the improved and practical bilayer tablet technology. In order to solve common bilayer issues such layer separation, inadequate hardness, imprecise individual layer control of weight, and cross contamination, this article discusses why Development and production of quality bi-layer tablets must be carried out on unique tablet presses due to issues with the layers, decreased yield, etc. thereby a high production output is needed, utilizing an altered tablet press may not be the best choice for producing a superior bilayer tablet under GMP conditions.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 64%
Pharmacology and Nanomedicine Research
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Formulation And Assessment of Oral Gel for The Treatment of Mouth Ulcer Using Extract from Jamun Seed Powder · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS