Formulation And Evaluation of Watermelon Seeds Loaded Spherules as Nutraceuticals

This research investigates the development of watermelon seed-loaded spherules as a potential delivery system for nutraceutical applications. Watermelon seeds are abundant in beneficial bioactive compounds such as polyphenols, essential fatty acids, and antioxidants, which have been associated with various health advantages, including anti-inflammatory and antioxidant effects. The goal of this study was to create spherules encapsulating watermelon seed and assess their physicochemical and their property to improve the health. The formulation process involved incorporating watermelon seed into spherules using biocompatible materials, with several preparation techniques being explored. The main objective of study is to formulate the spherules and fill in the capsules and carryout Phytochemical analysis which indicated the presence of various active compounds, such as flavonoids, alkaloids, and saponins, which are reported to possess therapeutic properties. Flow properties like angle of repose, bulk density, and Carr's index were analysed to assess the processability of the spherules and to maintain uniformity in the formulation of spherules and weight variation test and disintegration test shows the stability of the capsule.