Anthelmintic Potential of Carica Papaya Seed Extracts in Paediatric Candies: A Natural Remedy for Parasitic Infections

Parasitic infestations are an important cause of morbidity in children and are regarded as a serious public health hazard. Diseases generally caused by Ascaris Lumbricoides, Trichuris Trichura, and Hookworms have become a serious threat to the physical and cognitive development of children, particularly in areas lacking sanitation, hygiene, and ingestion of contaminated food and water. Parasites primarily cause diarrhea, abdominal pain, vomiting, lack of appetite, and abdominal distention; they can also cause iron deficiency anemia in pediatrics. Moreover giving medications to children can sometimes become a traumatic experience for the child and parents as they refuse to accept its taste and are already suffering from pain and discomfort. Recently there has been a growing interest in using plant constituents for drug development and treatments due to their natural medical properties. Studies suggest that papaya (Carica Papaya) seeds possess potent anthelmintic properties containing the primary compound Benzyl Isothiocyanate makes it a promising natural alternative for treating helminths. This research focuses on developing a child-friendly candy formulation incorporating C.papaya seed extract, rich in benzyl isothiocyanate offering an alternative drug delivery system aimed at medication compliance among pediatric patients. This research sheds important light on the possible applications of C. papaya seeds and a practical solution for treating children with helminth infection. This approach could improve deworming and is affordable and sustainable in resources-- limited settings