A Novel Alternative Therapeutic Strategies To Tackle Antibiotic Resistance

Antibiotics are considered one of the most significant discoveries of the twentieth century. However, the careless use of antibiotics in humans and animals has led to the rapid emergence of antibiotic-resistant microorganisms. In recent years, antibiotic resistance has become a global concern, contributing significantly to mortality rates and economic crises. Addressing this issue requires urgent exploration and development of innovative solutions. Solely relying on new drugs will not suffice to resolve the problem of antibiotic resistance. This article examines the causes and mechanisms underlying antimicrobial resistance (AMR) and its detrimental effects due to widespread prevalence. Furthermore, it highlights alternative approaches that hold potential in managing and mitigating AMR. These include Phage therapy, antimicrobial peptides, antimicrobial polymer and endophytes. Such strategies could offer promising ways to improve human and animal health while reducing unnecessary antibiotic use. Collaboration among governments, institutions, and regulatory bodies is essential to develop innovative approaches targeting antibiotic resistance and improving antibiotic effectiveness.