Phytochemical Identification and Formulation, Evaluation of Herbal Gel

The present work was carried out to manufacture and assess polyherbal gel formulation containing extracts of Tridax procumbens leaves and Curcuma amada rhizomes and Lagenaria siceraria fruit, utilizing carbopol as gelling agents. Six batches in total (FG1–FG6) were made and tested for physicochemical properties that were determined to be within the range, including pH, viscosity, spreadability, and drug content. Every formulation that was produced showed good physical stability. For the results showed that the optimized batch formulation had a percentage flavonoid release of 33.6% and a percentage phenol release of 32.32% after some hours. The Excision model was used to test the wound healing properties. Excellent inhibitory action was demonstrated by the produced mixture. Based on the findings, we deduced that ridax procumbens leaves and Curcuma amada rhizomes and Lagenaria siceraria, herbal drugs, have been found to be beneficial for healing the wound when taken in a polyherbal topical gel formulation.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-05-16
DOI
https://doi.org/10.5281/zenodo.15430701
Primary Topic
Pharmacology and Nanomedicine Research
Type
article
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article

Phytochemical Identification and Formulation, Evaluation of Herbal Gel

Zenodo (CERN European Organization for Nuclear Research)
Pharmacology and Nanomedicine Research
article

Phytochemical Identification and Formulation, Evaluation of Herbal Gel

article en

Abstract

The present work was carried out to manufacture and assess polyherbal gel formulation containing extracts of Tridax procumbens leaves and Curcuma amada rhizomes and Lagenaria siceraria fruit, utilizing carbopol as gelling agents. Six batches in total (FG1–FG6) were made and tested for physicochemical properties that were determined to be within the range, including pH, viscosity, spreadability, and drug content. Every formulation that was produced showed good physical stability. For the results showed that the optimized batch formulation had a percentage flavonoid release of 33.6% and a percentage phenol release of 32.32% after some hours. The Excision model was used to test the wound healing properties. Excellent inhibitory action was demonstrated by the produced mixture. Based on the findings, we deduced that ridax procumbens leaves and Curcuma amada rhizomes and Lagenaria siceraria, herbal drugs, have been found to be beneficial for healing the wound when taken in a polyherbal topical gel formulation.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 64%
Pharmacology and Nanomedicine Research
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