To Determine the Lipoprotein (A) Levels in Patients of Acute Coronary Syndrome

Introduction: High levels of lipoprotein(a) [Lp(a)] are associated with increased risk of acute coronary syndrome (ACS). We explored whether Lp(a) exhibits a stronger association with ACS. Methods: Hospital based cross-sectional study. Was conducted on 100 patients with acute coronary acute coronary syndrome (ACS). The serum lipo-protein(A) level was measure and ECG was done at the time of admission and repeated, as necessary. Lp (a) was measure by agglutination. Results: 49.00% patients were belong to age group 41-60 Yrs followed by 47.00% patients were more than 60 Yrs age group. 53.00% patients were male, and 47.00% patients were female. 50.00% patients were belong to middle socio-economic status and 40.00% patients were belong to upper socio-economic status. 58.00% patients were obese followed by 37.00% patients BMI was normal, and 5.00% patients were morbid obesity.31.00% patients were present with positive family history. 36.00% patients were present with positive smoking history. 30.00% patients were present with positive Tobacco chewing history. 25.00% patients were present with positive alcohol history. SBP was 128.02±11.06 mm of hg and DBP was 80.02±8.01 mm of hg. FBS was 110.06±19.36 mg/dl and PPBS was 165.39±34.02 mg/dl. Serum cholesterol was 185.36±43.28 mg/dl, Serum triglyceride was 151.23±60.35 mg/dl, LDL was 107.58±36.24 mg/dl and HDL was 44.23±7.14 mg/dl. lipo-a was 51.77±11.23mg/dl. The association between age and lipo-protein a level was found statistically significant. The association between sex and lipo-protein a level was found statistically Insignificant. Conclusion: Lp(a) seems to be an independent risk factor for acute coronary syndrome (ACS), and high Lp(a) levels increased the risk for acute coronary syndrome (ACS).