Toxicological Evaluation of Cassia occidentalis Leaf Extracts: Unveiling the Safety Profile of a Traditional Remedy

People assume that ayurvedic medications have fewer adverse effects than allopathic medications. Our study must determine the toxicity of the medicinal plants to ensure the safety of using these plants and their preparations (in gel and powder form). The aim of this study was to evaluate the acute toxicity of Cassia occidentalis leaves for medicinal purposes. Swiss mice received an oral dose of 2000 mg/kg body weight in the acute toxicity investigation. The different Cassia occidentalis extracts were administered orally to Swiss mice in a single dose then recorded the changes in body weight, food and water intake, and observations from the cage side. Our study revealed that the plant material was non-toxic.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-09-18
DOI
https://doi.org/10.5281/zenodo.13784635
Primary Topic
Phytochemistry and biological activity of medicinal plants
Type
article
Field-Weighted Citation Impact
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article

Toxicological Evaluation of Cassia occidentalis Leaf Extracts: Unveiling the Safety Profile of a Traditional Remedy

Zenodo (CERN European Organization for Nuclear Research)
Phytochemistry and biological activity of medicinal plants
article

Toxicological Evaluation of Cassia occidentalis Leaf Extracts: Unveiling the Safety Profile of a Traditional Remedy

article en

Abstract

People assume that ayurvedic medications have fewer adverse effects than allopathic medications. Our study must determine the toxicity of the medicinal plants to ensure the safety of using these plants and their preparations (in gel and powder form). The aim of this study was to evaluate the acute toxicity of Cassia occidentalis leaves for medicinal purposes. Swiss mice received an oral dose of 2000 mg/kg body weight in the acute toxicity investigation. The different Cassia occidentalis extracts were administered orally to Swiss mice in a single dose then recorded the changes in body weight, food and water intake, and observations from the cage side. Our study revealed that the plant material was non-toxic.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 79%
Phytochemistry and biological activity of medicinal plants
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