Differential Expression of NOTCH1 gene in Head and Neck Squamous Cell Carcinoma: Impact of Gender, HPV Status, and Tumour Stage"

Head and neck squamous cell carcinomas (HNSCC) constitute a heterogeneous group of cancers, which include cancers arising at the oral cavity, nasopharynx, oropharynx, hypopharynx, and larynx. This was a Prospective and observational studies in head and neck cancer patients Cohort – 60 cases of head and neck cancers (20 cases of Tongue; 20 cases of Epiglottis; 20 cases of hard palate) conducted at Malla Reddy Medical college and tertiary care hospitals in Hyd erabad. Adults aged ≥ 18 years diagnosed with head and neck cancer (HNC). (C)RT patients discussed in a Head and Neck MDT meeting and deemed medically fit for an agreed treatment plan for primary or adjuvant radiotherapy ± concurrent or induction chemotherapy (cisplatin or cetuximab)