HARNESSING NATURE AND TECHNOLOGY: ROLE OF HERBAL CONSTITUENTS AND NANOTECHNOLOGY IN THE MANAGEMENT OF PSORIASIS

Psoriasis is a chronic, non-communicable, autoimmune skin disorder characterized by red, scaly plaques, primarily affecting the elbows, knees, scalp, and lower limbs. Its pathogenesis involves complex immune dysregulation, notably through T-cell activation, cytokine overexpression (such as TNF-α, IL-17, and IL-23), and aberrant keratinocyte proliferation.