Functional Role of Lactoferrin in Intestinal Health and Inflammatory Bowel Disease

<p><span>A chronic illness that causes inflammation in the digestive tract is called inflammatory bowel disease (IBD). It is brought on by the immune system of the body targeting healthy intestinal cells. Ulcerative colitis and Crohn's disease are two forms of IBD. Risk elements Age, environmental factors that impact the gut microbiome, and family history of IBD. Lactoferrin is frequently measured in stool samples as a marker for disease activity, with higher levels indicating increased inflammation in the colon. Lactoferrin functions as a potential anti-inflammatory agent in ulcerative colitis, primarily by binding to iron and limiting its availability to harmful bacteria, thereby reducing inflammation in the intestinal lining. We hope this information will provide a reference for future studies and lay a theoretical foundation for LF-based therapeutic interventions for IBD by understanding the particular effects of LF on intestine mucosal immune system.</span></p>