Association between High-Sensitivity C-Reactive Protein (Hs-Crp) And Acute Ischemic Stroke: A Case-Control Study

Background and Objectives: Acute ischemic stroke (AIS) is a leading cause of morbidity and mortality worldwide. Inflammation plays a crucial role in the pathogenesis of AIS. High-sensitivity C-reactive protein (HS-CRP) is a sensitive marker of inflammation. Use of serum markers has been a established practice in medicine. CRP levels have been known to provide a estimate of inflammation. The present study was formulated to ascertain if levels of CRP in acute ischaemic stroke cases can be a prognostic or diagnostic marker for the condition. Methods: The study was a prospective case control format and utilized a subject pool of 50 subjects as case and control each. The study observed a significantly elevated level of CRP in cases with an acute ischaemic stroke. The study concluded that use of CRP can be a an effective modality in clinical practice in managing such cases. To investigate the relationship between HS-CRP levels and AIS. To evaluate the predictive value of HS-CRP for AIS. To examine the association between HS-CRP and stroke severity.