Formulation And Evaluation of Herbal Tablets Using Nyctanthes Arbor Tristis Leaves Powder
The formulation and evaluation of herbal tablets using Nyctanthes arbor-tristis (Nightflowering Jasmine) powder through wet granulation involves a multi-step process aimed at ensuring the tablets' efficacy, stability, and safety.The process begins with the thorough characterization of Nyctanthes arbor-tristis powder to understand its phytochemical composition and identify active compounds responsible for its medicinal properties. Suitable excipients are then selected based on their compatibility with the herbal powder and their ability to aid in granulation and tablet formation. Wet granulation involves mixing the Nyctanthes arbor-tristis powder with wetting agents and binders to form granules. The wet mass is then passed through a sieve to produce uniform granules of the desired size. These granules are then dried to remove excess moisture, ensuring stability during storage. The dried granules are then mixed with additional excipients such as disintegrants and lubricants to improve tablet characteristics and aid in the compression process. The mixture is compressed into tablets using tablet presses, forming tablets of consistent weight and hardness.The formulated tablets undergo evaluation for various parameters including weight variation, hardness, friability, disintegration time, and dissolution rate. These tests ensure that the tablets meet pharmacopoeial standards and requirements for quality and performance.
Publication Details
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Published
- 2025-06-10
- DOI
- https://doi.org/10.5281/zenodo.15628332
- Primary Topic
- Pharmacology and Nanomedicine Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00