Preparation And Application of Liposome

Made of the same substance as a cell membrane, a liposome is a tiny bubble, or vesicle. Drugs for cancer and other illnesses can be delivered using liposomes that have been loaded with medication. At the Babraham Institute in Cambridge, British haematologist Dr. Alec D. Bangham FRS initially described liposomes in 1961 (published 1964). They were found when Bangham and R. W. Horne added negative stain to dry phospholipids in order to test the institute's new electron microscope. The microscope images provided the first concrete proof that the cell membrane is a bilayer lipid structure, and the likeness to the plasmalemma was evident. The Greek terms "Lipos," which means fat, and "Soma," which means body, are the origin of the term "liposome."(7) This bibliographic study provides a broad overview of the history and evolution of liposomes, emphasizing both traditional (ethanol injection, reverse-phase evaporation, thin film hydration) and innovative scalable methods of manufacture. Liposomes' use in the food, cosmetics, and pharmaceutical industries as prospective new discoveries and products were also discussed, as well as the present growth and expansion of interest in them across numerous scientific fields. The effectiveness of liposomes in a variety of applications is finally discussed, with opinions ranging from unjustified pessimism to unsupported optimism. (1).