To Study the Antibacterial Activity of Grape Seeds

The strong polyphenolic content and related health advantages of grape seed extract (GSE), which is derived from Vitis vinifera are well- known1. GSE's antibacterial efficacy against Gram-positive (Bacillus subtilis) and Gram-negative (Escherichia coli) bacteria is assessed in this study utilizing the agar well diffusion method2. The extract showed 12 mm inhibition zones against both strains, indicating modest antibacterial activity3. In contrast to the typical antibiotic Metronidazole (25–26 mm zones), GSE exhibited less pronounced but nonetheless noteworthy inhibitory effects4. These results provide credence to GSE's possible application as a natural antibacterial.