Synthesis, Characterization and It's Antimicrobial Activity of Probenecid

Probenecid was created by reacting 4-carboxybenzene sulfonamide with di-n-propylamine [1]. By promoting the excretion of uric acid, this uricosuric drug is used to treat hyperuricemia and gout [1]. The procedure creates probenecid by creating an amide link between the amine and the sulfonamide [2].

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-06-07
DOI
https://doi.org/10.5281/zenodo.15614513
Primary Topic
Enzyme function and inhibition
Type
article
Field-Weighted Citation Impact
0.00
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article

Synthesis, Characterization and It's Antimicrobial Activity of Probenecid

Zenodo (CERN European Organization for Nuclear Research)
Enzyme function and inhibition
article

Synthesis, Characterization and It's Antimicrobial Activity of Probenecid

article en

Abstract

Probenecid was created by reacting 4-carboxybenzene sulfonamide with di-n-propylamine [1]. By promoting the excretion of uric acid, this uricosuric drug is used to treat hyperuricemia and gout [1]. The procedure creates probenecid by creating an amide link between the amine and the sulfonamide [2].

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 60%
Enzyme function and inhibition
DOIOpen Access PDFOpenAlex
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Synthesis, Characterization and It's Antimicrobial Activity of Probenecid · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS