Comprehensive Phytochemical Profiling And Therapeutic Applications Of Plecospermum Spinosum Trecul: An Endangered Medicinal Plant

The Moraceae family includes the medicinal herb Plecospermum spinosum Trecul. In colloquial Tamil, it is called "Korratimul" and is an endangered species of medicinal plant. The goal of the current study was to learn more about this plant's possible medical applications, including as its capacity to fight infections and cure a range of ailments. The antibacterial, antioxidant, and antimicrobial properties of the plant's methanolic extract were evaluated against a variety of pathogens, including Proteus vulgaris, Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli, Shigella Flexheri, and Streptococcius mutants. Gas chromatography-mass spectrometry (GC-MS) was also used to quantify the plant's phenolic compounds, flavonoids, saponins, tannins, sterols, sugars, and free amino acids. 35 distinct phytochemical components, including flavonoids (164.88, 1.1, and 1.12 mg/mg) and triterpenoids (70.34, 2.1, and 164.28 mg/g) as well as other bioactive phytochemicals, were found in the ethanolic leaf extract after phytochemical screening. The extract's noteworthy medicinal potential is further highlighted by the antibacterial and antioxidant activities found in it. This thorough examination provides a promising route for the discovery of natural cures and the preservation of biological resources, as well as for future research and development.