Formulation and Evaluation of Sustained Release Pellets of Oral Antidiabetic Agent by Using Natural Polymer

In the present study we concluded that, the formulation and assessment of sustained release tablets utilizing natural polymers are the main topics of the review. Long-term medication release is the goal of sustained release (SR) dose forms, which increase patient compliance and therapeutic efficacy. The benefits and drawbacks of sustained release tablets are covered in the study along with preparation techniques and the many natural polymers that are utilized in these formulations. Natural polymers that have been shown to improve drug release characteristics include chitosan, starch, cellulose, xanthan gum, guar gum, and gum karaya. Evaluation tests for sustained release tablets are also covered in the study, including testing for in-vitro dissolution, thickness, diameter, weight fluctuation, hardness, friability, and content homogeneity. According to the results, prolonged release tablets specially those made of natural polymers offer a number of advantages over traditional dose forms with regard to patient adherence and regulated drug administration.