A Comprehensive Review on Formulation Development of Salicylic Acid Ointment

A 6% salicylic acid ointment was formulated for multipurpose use in skincare, particularly targeting conditions such as acne, blackheads, psoriasis, corns, and callus. The ointment was prepared using salicylic acid powder, petroleum jelly, and glycerine as the base. The primary goal of the formulation was to utilize the keratolytic properties of salicylic acid for effective skin treatment. The prepared ointment underwent various evaluation test to assess its quality. The results indicated that the formulation had an appropriate pH, good spreadability, suitable viscosity, uniform appearance, and showed no signs of phase separation. Furthermore, the ointment did not cause any skin irritation upon application. Based on these findings, the formulated salicylic acid ointment was concluded to be stable, effective, and safe for topical use.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-04-30
DOI
https://doi.org/10.5281/zenodo.15308852
Primary Topic
Advancements in Transdermal Drug Delivery
Type
article
Field-Weighted Citation Impact
0.00
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article

A Comprehensive Review on Formulation Development of Salicylic Acid Ointment

Zenodo (CERN European Organization for Nuclear Research)
Advancements in Transdermal Drug Delivery
article

A Comprehensive Review on Formulation Development of Salicylic Acid Ointment

article en

Abstract

A 6% salicylic acid ointment was formulated for multipurpose use in skincare, particularly targeting conditions such as acne, blackheads, psoriasis, corns, and callus. The ointment was prepared using salicylic acid powder, petroleum jelly, and glycerine as the base. The primary goal of the formulation was to utilize the keratolytic properties of salicylic acid for effective skin treatment. The prepared ointment underwent various evaluation test to assess its quality. The results indicated that the formulation had an appropriate pH, good spreadability, suitable viscosity, uniform appearance, and showed no signs of phase separation. Furthermore, the ointment did not cause any skin irritation upon application. Based on these findings, the formulated salicylic acid ointment was concluded to be stable, effective, and safe for topical use.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 62%
Advancements in Transdermal Drug Delivery
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