BOTULINUM TOXIN IN THE MANAGEMENT OF HYPERHIDROSIS: ADVANCES AND CLINICAL IMPLICATIONS

Botulinum toxin (BT) is widely used in the treatment of neuromuscular and aesthetic conditions, including hyperhidrosis, which is characterized by excessive sweating. This study aims to review the application of BT in the treatment of hyperhidrosis, exploring its mechanisms of action and clinical efficacy. A review was conducted through the analysis of scientific articles that address the use of BT in hyperhidrosis, with a focus on clinical studies and systematic reviews. Hyperhidrosis can be classified as primary or secondary, significantly affecting patients' quality of life. BT, by blocking the release of acetylcholine at neuromuscular junctions, offers an effective therapeutic option for this condition. The application of BT has proven to be effective in reducing sweating in various regions of the body, such as the axillae, palms, soles, and face. Studies have shown that BT can significantly reduce sweat production, improving patients' quality of life. However, the effects of BT are temporary, lasting from 4 to 12 months, which necessitates periodic reapplications. BT is an effective and safe therapeutic alternative for the treatment of hyperhidrosis, providing temporary relief of symptoms and improving patients' quality of life. Further studies are needed to optimize dosage and intervals between applications, as well as to assess the long-term effects of this intervention.