Emerging approaches to genetic therapy in treatment for breast cancer

Breast cancer is one of the leading causes of death among women, which implies an urgent need to explore further alternative therapeutic strategies than conventional surgery, chemotherapy, and radiotherapy treatments. Thus, prevention should be highlighted through early genetic screening, not only among patients with clear risk factors but also among the general population in order to discover predisposition and intervene earlier. The current therapeutic innovations are focused on improving such treatments by devising less invasive and more specific approaches. Examples include gene repair, such as halting tumor growth by restoring functionality to damaged genes using CRISPR and similar technologies. MicroRNAs have also shown much promise in controlling major cancer processes such as metastasis and cell division. Besides, nanoparticle-based drug delivery allows for more effective release of drugs. Consequently, there is lesser development of side effects. Suicide gene therapy is also commanding more attention against breast cancer as a less aggressive and hence more effective therapy with the appearance of selective killing of cancerous cells.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-11-30
DOI
https://doi.org/10.5281/zenodo.14821377
Primary Topic
Virus-based gene therapy research
Type
article
Field-Weighted Citation Impact
0.00
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article

Emerging approaches to genetic therapy in treatment for breast cancer

Zenodo (CERN European Organization for Nuclear Research)
Virus-based gene therapy research
article

Emerging approaches to genetic therapy in treatment for breast cancer

article en

Abstract

Breast cancer is one of the leading causes of death among women, which implies an urgent need to explore further alternative therapeutic strategies than conventional surgery, chemotherapy, and radiotherapy treatments. Thus, prevention should be highlighted through early genetic screening, not only among patients with clear risk factors but also among the general population in order to discover predisposition and intervene earlier. The current therapeutic innovations are focused on improving such treatments by devising less invasive and more specific approaches. Examples include gene repair, such as halting tumor growth by restoring functionality to damaged genes using CRISPR and similar technologies. MicroRNAs have also shown much promise in controlling major cancer processes such as metastasis and cell division. Besides, nanoparticle-based drug delivery allows for more effective release of drugs. Consequently, there is lesser development of side effects. Suicide gene therapy is also commanding more attention against breast cancer as a less aggressive and hence more effective therapy with the appearance of selective killing of cancerous cells.

Zenodo (CERN European Organization for Nuclear Research)
Universidad Juárez del Estado de Durango (MX)
Good health and well-being
Openalex Percentile: Top 64%
Virus-based gene therapy research
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