Implication of Platelet Indices in Seropositive Dengue Patients in Tertiary Care Hospital in Uttar Kannada District

Background: Thrombocytopenia is the most common laboratory finding in dengue fever with considerable morbidity and mortality. Platelet indices have been investigated as platelet activation marker and MPV can be used as independent predictor of bleeding. Objectives: To assess the correlation of platelet indices with platelet count in seropositive dengue patients. Methods: A retrospective study was done in Karwar Institute of Medical Sciences, Karwar for a period of 6 months from Jan 2024 to June 2024. Serologically confirmed dengue cases were included and platelet parameters for continuous 3 days from day of admission were noted. Results: A total of 180 dengue seropositive samples were studied. Mean PDW, MPV, P-LCR and PCT across 5 groups of platelet count were compared and showed a significant difference with p<0.001. Conclusion: Platelet indices play a significant role in early predictive diagnosis. PDW, P-LCR, MPV had an inverse relation with platelet count and PCT was directly proportional to platelet count.