Effectiveness of Moringa Oleifera Extract in Type II Diabetes: A Comprehensive Literature Review

Moringa oleifera, also known as the miracle tree, is considered nutritionally rich with therapeutic properties. This article emphasizes the phytochemicals and their therapeutic potential in the management of Type II diabetes. This study aims to provide a comprehensive understanding of Moringa oleifera's contributions to the management of diabetes. Nowadays, attention has been drawn towards Moringa for its potential to manage oxidative stress and inflammation associated with Type II diabetes. In this review article, we included various scientific studies to establish a link between the effect of moringa extracts on metabolic parameters and Type II diabetes. The studies indicated that Moringa extracts improve glucose tolerance and insulin signaling. It is seen that the moringa extracts can reduce plasma insulin levels and pro-inflammatory cytokines. Experimental models such as high-fat diet-fed and streptozocin-induced diabetic animals have shown decreased fasting glucose levels and improved lipid profiles on the administration of Moringa extracts. In addition, it has demonstrated improvements in body weight and a decrease in inflammatory markers in obese and diabetic animal models. Furthermore, the extract has shown effectiveness in wound healing and improved insulin sensitivity, which indicates its multifaceted use in diabetes management. In a nutshell, the findings of scientific research indicate that Moringa extracts can be used for managing Type II diabetes. However, there is a need for more extensive research to fully understand and elucidate the mechanism of action and clinical implications of Moringa oleifera in diabetes.