Nanoemulsions: A Promising Technology For The Development Of Innovative Products

Nanoemulsions are submicron-sized emulsions under extensive investigation as drug carriers for improving the delivery of therapeutic agents. They are the most advanced nanoparticle systems for the systemic delivery of biologically active agents for controlled drug delivery and targeting. Nanoemulsions are thermodynamically stable isotropic systems formed by mixing two immiscible liquids (water and oil) with suitable surfactants or their mixture to obtain a single phase with a droplet diameter ranging from 0.5 to 100 um. The size distributions of nanoemulsion droplets are narrow and usually lie between 20 and 200 nm. Nanoemulsions possess significant potential for advancing cosmetics, diagnostic tests, medicinal therapies, and biotechnology. This review aims to provide a concise overview of the investigation of the formulation, preparation process, and characterization techniques of nanoemulsions. It especially emphasizes the diverse applications of nanoemulsions in several fields including cancer treatment, drug targeting, mucosal vaccination, transdermal drug delivery, lipophilic drug delivery, self-nano emulsifying, and solid self-nano emulsifying drug delivery systems.