Relationship between Prevalence of Microalbuminuria to Target Organ Damage in Essential Hypertensive Patients: A Hospital Based Observational Study

Background: Age, obesity, diabetes, insulin resistance, and dyslipidemia are cardiovascular risk factors that are typically associated with essential hypertension. Early in the course of hypertension, subtle target organ damage occurs, including left ventricular hypertrophy, microalbuminuria, and cognitive impairment. We assessed the correlation between target organ damage and the occurrence of microalbuminuria in patients with essential hyper-tension. Methods: 60 patients with essential hypertension in total were examined. The prevalence of albumin excretion in the urine and its relationship to damage to the target organs (stroke, retinopathy, and left ventricular hyper-trophy) were examined. Microalbuminuria was measured using the urine albumin to creatinine ratio, and urinary albumin excretion was measured using the turbidimetry method. Results: A total of 57.5% of the patients had microalbuminuria. 82.5% of patients had concomitant microal-buminuria (p <0.05), and 82.82% of patients had target organ damage. Patients with longer duration and more severe cases of hypertension, elevated body mass index, and dyslipidemia were shown to have a higher preva-lence among them. Conclusion: An essential diagnostic for assessing target organ damage in hypertension individuals is the meas-urement of microalbuminuria. The risk of microalbuminuria is reduced by maintaining normal lipid levels, con-trolling weight, and managing hypertension as best as possible.

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Zenodo (CERN European Organization for Nuclear Research)
Published
2024-11-26
DOI
https://doi.org/10.5281/zenodo.14599240
Primary Topic
Chronic Kidney Disease and Diabetes
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article
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article

Relationship between Prevalence of Microalbuminuria to Target Organ Damage in Essential Hypertensive Patients: A Hospital Based Observational Study

Zenodo (CERN European Organization for Nuclear Research)
Chronic Kidney Disease and Diabetes
article

Relationship between Prevalence of Microalbuminuria to Target Organ Damage in Essential Hypertensive Patients: A Hospital Based Observational Study

article en

Abstract

Background: Age, obesity, diabetes, insulin resistance, and dyslipidemia are cardiovascular risk factors that are typically associated with essential hypertension. Early in the course of hypertension, subtle target organ damage occurs, including left ventricular hypertrophy, microalbuminuria, and cognitive impairment. We assessed the correlation between target organ damage and the occurrence of microalbuminuria in patients with essential hyper-tension. Methods: 60 patients with essential hypertension in total were examined. The prevalence of albumin excretion in the urine and its relationship to damage to the target organs (stroke, retinopathy, and left ventricular hyper-trophy) were examined. Microalbuminuria was measured using the urine albumin to creatinine ratio, and urinary albumin excretion was measured using the turbidimetry method. Results: A total of 57.5% of the patients had microalbuminuria. 82.5% of patients had concomitant microal-buminuria (p <0.05), and 82.82% of patients had target organ damage. Patients with longer duration and more severe cases of hypertension, elevated body mass index, and dyslipidemia were shown to have a higher preva-lence among them. Conclusion: An essential diagnostic for assessing target organ damage in hypertension individuals is the meas-urement of microalbuminuria. The risk of microalbuminuria is reduced by maintaining normal lipid levels, con-trolling weight, and managing hypertension as best as possible.

Zenodo (CERN European Organization for Nuclear Research)
Darbhanga Medical College and Hospital (IN)
Good health and well-being
Openalex Percentile: Top 57%
Chronic Kidney Disease and Diabetes
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