Culture and Sensitivity Patterns in Surgical Site Infections at Government General Hospital, Nizamabad: A Prospective Study

Background: Surgical site infection is one of the leading cause of Hospital acquired infections in developing countries. Surgical site infection rates ranges from 0.5% to 15% globally, 23% to 38% in India.7 Hence identification of bacterial pathogens and their antibiotic susceptibility testing is required for successful treatment of SSI. Aim & Objectives: To evaluate the bacterial spectrum, antibiotic sensitivity pattern and drug resistance Of isolated organisms in surgical site infections. Materials and Methods: Total of 110 pus samples were collected over a period of one year from surgical site infections. Detection of Organisms was done by Conventional culture and Biochemical methods, antibiotic sensitivity pattern of the isolates was studied by Kirby-bauer disc diffusion technique following CLSI guidelines. Results: Of the 110 clinical isolates 28 (25.45%) were pus/swab culture positive. Gram Positive organisms 15 (53.57%) were the predominant causative agents of SSI compared to Gram negative organisms 13 (46.42%) in the cases. Prevalence of MRSA is 9 (86%) of the isolated Staphylococcus aureus. ESBL production was observed in 6 (46.1%), MBL production was observed in 2(15.38%) of Gram negative isolates. Conclusion: The study gives an insight into bacterial pathogens and their antibiotic sensitivity patterns isolated from SSI. Preparation of antibiogram suitable for the hospital and its strict implementation is required in order to prevent antimicrobial resistance (AMR).