RELATIONSHIP SPIROMETRY VALUES AND DIABETES CONTROL IN TYPE 2 DIABETES MELLITUS PATIENTS

Abstract Background: Diabetes mellitus (DM) is a chronic disorder with persistently elevated blood glucose levels that leads to the development of microvascular and macrovascular complications over several years. The bidirectional relationship between DM and the lungs is clinically proven to have progressive pulmonary function abnormalities with decreased Forced Expiratory Volume in 1 second (FEV1) and Forced Vital Capacity (FVC) in individuals with poor DM control. Methods: This study was an observational analytic study using a Case Control approach method in patients with Diabetes Mellitus at Pangkajene Health Center. Each research subject underwent spirometry examination. Results: This study involved 133 research subjects, consisting of 3 groups, uncontrolled diabetes mellitus patients 38.2%, controlled 36.6%, and control group 25.2%. The mean age was 60.13 ± 9.82, 40 males and 91 females. The mean HbA1c value was 8.55 ± 1.69. Spirometric examinations were performed on all groups with parameters of Forced Vital Capacity (FVC), Forced Expiratory Volume in the first second (FEV1), and FEV1/FVC ratio. The mean Forced Vital Capacity (FVC) value in all samples was 73.65%, the mean Forced Expiratory Volume in the first second (FEV1) value was 60.47%, and the mean FEV1/FVC value was 86.25%. Conclusion: There was a significant weak negative correlation between HbA1c and FVC and FEV1 in uncontrolled DM patients. This indicates that the higher the HbA1c value, the lower the FVC and FEV1 values will be.