FORMULATION AND EVALUATION OF CLOVE BASED CHEWABLE TABLET FOR TOOTHACHE MANAGEMENT

Clove, with its rich medicinal properties, has genereted significant attention in pharmaceutical formulations. This study presents the development of a clove-formulated chewable tablet using the wet granulation method, aimed to enhancing patient compliance and bioavailability. The formulation process involved the selection of excipients conducive to chewable tablet characteristics and the optimization of clove extract concentration to achieve desired therapeutic effects. Physicochemical properties, such as hardness, friability, disintegration time, and dissolution profile, were evaluated to ensure the tablet's robustness and efficacy. Results indicate that the wet granulation method offers a promising approach for the development of clove-based chewable tablets with improved taste masking, enhanced stability, and optimized drug release profile. This research contributes to the advancement of herbal medicine formulations, offering a convenient and effective dosage form for clove-based therapeutics.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-08-10
DOI
https://doi.org/10.5281/zenodo.13293039
Primary Topic
Drug Solubulity and Delivery Systems
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

FORMULATION AND EVALUATION OF CLOVE BASED CHEWABLE TABLET FOR TOOTHACHE MANAGEMENT

Zenodo (CERN European Organization for Nuclear Research)
Drug Solubulity and Delivery Systems
article

FORMULATION AND EVALUATION OF CLOVE BASED CHEWABLE TABLET FOR TOOTHACHE MANAGEMENT

article en

Abstract

Clove, with its rich medicinal properties, has genereted significant attention in pharmaceutical formulations. This study presents the development of a clove-formulated chewable tablet using the wet granulation method, aimed to enhancing patient compliance and bioavailability. The formulation process involved the selection of excipients conducive to chewable tablet characteristics and the optimization of clove extract concentration to achieve desired therapeutic effects. Physicochemical properties, such as hardness, friability, disintegration time, and dissolution profile, were evaluated to ensure the tablet's robustness and efficacy. Results indicate that the wet granulation method offers a promising approach for the development of clove-based chewable tablets with improved taste masking, enhanced stability, and optimized drug release profile. This research contributes to the advancement of herbal medicine formulations, offering a convenient and effective dosage form for clove-based therapeutics.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 70%
Drug Solubulity and Delivery Systems
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.