FORMULATION AND EVALUATION OF CLOVE BASED CHEWABLE TABLET FOR TOOTHACHE MANAGEMENT
Clove, with its rich medicinal properties, has genereted significant attention in pharmaceutical formulations. This study presents the development of a clove-formulated chewable tablet using the wet granulation method, aimed to enhancing patient compliance and bioavailability. The formulation process involved the selection of excipients conducive to chewable tablet characteristics and the optimization of clove extract concentration to achieve desired therapeutic effects. Physicochemical properties, such as hardness, friability, disintegration time, and dissolution profile, were evaluated to ensure the tablet's robustness and efficacy. Results indicate that the wet granulation method offers a promising approach for the development of clove-based chewable tablets with improved taste masking, enhanced stability, and optimized drug release profile. This research contributes to the advancement of herbal medicine formulations, offering a convenient and effective dosage form for clove-based therapeutics.
Publication Details
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Published
- 2024-08-10
- DOI
- https://doi.org/10.5281/zenodo.13293039
- Primary Topic
- Drug Solubulity and Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 0.00